Matrixyl® 3000 Serum | Pouches is a single-use, travel-ready peptide serum from Timeless Skin Care that targets fine lines and early signs of aging while restoring firmness, elasticity, and hydration. Each box contains 28 single-use pouches (a one-month supply) priced at $20.95, with a formula built on Matrixyl® 3000—shown to boost collagen synthesis by up to 258%—plus 1% Hyaluronic Acid, aloe, and glycerin. It is fragrance-free, paraben-free, dye-free, sulfate-free, cruelty-free, and vegan, and is made in the USA in small batches. In a 14-day study of 24 participants ages 20–58 performed by a third party, 96% found improved skin firmness, 92% found their skin firmer and more elastic, and 92% agreed the skin of the face, neck, and décolleté looked visibly more youthful. The product is rated 4.9 out of 5 stars across 829 reviews.
Best for
- All skin types, especially sensitive skin
- Those new to anti-aging routines who want a gentle entry point
- Anyone targeting fine lines and early signs of aging without irritation
- Shoppers looking for a retinol alternative in a gentler format
- Travelers and on-the-go users who prefer single-use packaging
- Use on face, neck, and décolleté
How it compares
Within the Timeless line, Matrixyl® 3000 Serum is recommended for all skin types—especially sensitive skin and those getting started with anti-aging—targeting fine lines to help prevent early signs of aging. The Matrixyl® Synthe’6® Serum is instead recommended for dry and mature skin, focusing on deeper lines and wrinkles. Compared with retinol, the brand describes Matrixyl® 3000 as one of its retinol alternatives, providing similar benefits in a more gentle way, and notes both can be used in the same routine. This pouch version offers the same serum in new single-use packaging, which the page describes as perfect for travel and on-the-go use.
Frequently asked questions
- What is in it and what does it do? The formula contains Water, Matrixyl® 3000, Aloe Barbadensis, Glycerin, Hyaluronic Acid, Benzylalcohol, and Dehydroacetic Acid. Matrixyl® 3000 signals skin repair and collagen production, while Hyaluronic Acid hydrates and softens.
- How do I use it? Apply and smooth the contents of one single-use pouch onto freshly cleansed face and neck, wait until fully absorbed before the next step in your routine, and use daily—PM use is recommended for best results.
- How long does one box last? Each box contains 28 single-use pouches, a one-month supply. With the suggested daily use amount, the serum typically lasts about one month.
- What is the shelf life? For best results, use within 24 months of receipt; use upon receipt and refrigeration is suggested to assist with shelf life.
- Can I use it under my eyes? No—direct application to the under-eye area is not recommended. Use products specifically formulated for the delicate eye area instead.
- Is it safe during pregnancy? Yes, when used as directed. Review the ingredient list and consult your healthcare provider if needed. For external use on face and neck only; avoid eyes and chest/nipple area, and discontinue if irritation occurs.
- Can I use it with retinol? Yes. It is considered one of Timeless's retinol alternatives, and both can be used in the same routine to complement one another.
- What about shipping and returns? One-time purchases get free shipping on U.S. orders $75+, and subscription orders get free U.S. shipping with 20% off every order (pause, skip, or cancel anytime). One-time purchases are covered by "60 days happiness guaranteed or your money back." Full terms are on the FAQ page.
What customers say
Rated 4.9 out of 5 stars based on 829 reviews.
- "By far the best peptide serum I've used. It kicks my Botox into high gear. Try it!" — Kimberly S., Verified Buyer
- "Completely changed my skin! My skin is clearer and it is a way better substitute from retinol which is harsh." — Stephanie G., Verified Buyer
- "I've been using this for years. Love the great packaging. The product lasts a lot longer. My skin feels tighter and looks refreshed." — Denise S., Verified Buyer
Pairs well with
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